Phosphorylation- the Givers and the Takers
You’ll often hear that proteins are the ‘doers’ of the cell: DNA stores and passes information across generations, RNA is a messenger middle-man, but protein is where the action’s at.
Well, let me tell you that this is overly-simplified pro-protein propaganda (although maybe because my heart belongs to RNA). Because while proteins can do things, they often need a bit of help. Just because a protein is ‘there’, doesn’t mean that it’s active. Many proteins need to be literally chaperoned into the right 3-D structure, require other co-factors to do their job (like minerals and pigments), or only work when they’re part of a multi-protein complex.… Read more